ⓘ Glucose paradox. The glucose paradox was the observation that the large amount of glycogen in the liver was not explained by the small amount of glucose absorbe ..


ⓘ Glucose paradox

The glucose paradox was the observation that the large amount of glycogen in the liver was not explained by the small amount of glucose absorbed. The explanation was that the majority of glycogen is made from a number of substances other than glucose. The glucose paradox was first formulated by biochemists J. Denis McGarry and Joseph Katz in 1984.

The glucose paradox demonstrates the importance of the chemical compound lactate in the biochemical process of carbohydrate metabolism. The paradox is that the large amount of glycogen 10% found in the liver cannot be explained by the livers small absorption of glucose. After the bodys digestion of carbohydrates and the entering the circulatory system in the form of glucose, some will be absorbed directly into the muscle tissue and will be converted into lactic acid throughout the anaerobic energy system, rather than going directly to the liver and being converted into glycogen. The lactate is then taken and converted by the liver, forming the material for liver glycogen. The majority of the bodys liver glycogen is produced indirectly, rather than directly from glucose in the blood. Under normal physiological conditions, glucose is a poor precursor compound and use by the liver is limited.

  • such disease. Glucose paradox The large amount of glycogen in the liver cannot be explained by its small glucose absorption. Hispanic paradox The finding
  • The Australian Paradox is a term coined in 2011 to describe what its proponents say are diverging trends in sugar consumption and obesity rates in Australia
  • glucose concentrations, also known as blood sugar levels. When the glucose level is high, the beta cells secrete insulin into the blood when glucose
  • the glycemic index. Her books about the low GI diet, including The New Glucose Revolution, have sold more than two million copies since 1996. The most
  • of time. Plasma glucose is said to be maintained when there is an equal rate of glucose appearance entry into the blood and glucose disposal removal
  • that plays a role in cellular energy homeostasis, largely to activate glucose and fatty acid uptake and oxidation when cellular energy is low. It belongs
  • insulin response or insulin resistance leads to persistently high blood glucose concentrations. Diabetes affects up to 1 in 230 cats, and may becoming
  • of endogenous glucose production during hyperinsulinemic euglycemic glucose clamps: Comparison of unlabeled and labeled exogenous glucose infusates Diabetes
  • increased risk of fetal macrosomia and neonatal hypoglycemia. The blood glucose concentration in humans is mainly dependent on diet, especially energy - ingestion
  • neurons depolarize in response to high glucose concentrations. This mechanism seems to be related to glucose being used as a reactant to form ATP, which